Sinusitis develops in approximately 31 million Americans each year. "Parameters for the Diagnosis and Management of Sinusitis." Journal of Allergy and Clinical Immunology (1998) 102:S107-S144. People suffering from sinusitis miss an average of four days of work each year. "Parameters for the Diagnosis and Management of Sinusitis." Journal of Allergy and Clinical Immunology (1998) 102:S107-S144. There are more than 18 million office visits to primary care physicians resulting in a diagnosis of sinusitis annually. "Parameters for the Diagnosis and Management of Sinusitis." Journal of Allergy and Clinical Immunology (1998) 102:S107-S144. In 1996, overall health care expenditures attributable to sinusitis in the United States were estimated to be over $5.8 billion. Ray, N., Baraniuk, J., Thamer, M., Rinehart, C., Gergen P., Kaliner, M., Josephs, S., Pung, Y. "Healthcare expenditures for sinusitis in 1996: Contributions of asthma, rhinitis, and other airway disorders." Journal of Allergy and Clinical Immunology (1999) 103:408-14. There is an association between sinusitis and asthma. The incidence of sinusitis in asthmatic subjects ranges from 40 to 75%. "Parameters for the Diagnosis and Management of Sinusitis." Journal of Allergy and Clinical Immunology (1998) 102:S107-S144. *Adapted from the AAAAI